volume 161 number 1 Jenuary-February


Corr. Member of the Academy V. Kokilashvili

On Two-Weighted Compactness of Weak Singular Integrals on Curves

Presented July 5, 1999

Abstract. The simple two-weighted sufficient condition of compactness for integral transforms with weak singularity on regular curves is presented.

Key words: weak singular integral, two-weighted compactness, regular curves.

U. Goginava

Uniform Convergence of Cesaro Means of Negative Order of
N-dimensional Walsh-Fourier Series

Presented by Member of the Academy L. Zhizhiashvili, November 9, 1998

Abstract. In this paper we prove that if and the function f is of bounded partial variation, then the N-dimensional Walsh-Fourier series of the function f is uniformly summable in the sense of Pringsheim. If , then on there exists the continuous function f0 of bounded partial variation of which Cesaro means of N-dimensional Walsh-Fourier series of f will diverge over cubes.

Key words: uniform summability, Fourier series, Walsh functions.

Z. Kharebava

Perturbation Theory in the Cobar-Bar Resolution

Presented by Corr. Member of the Academy N. Berikashvili, December 28, 1998

Abstract. In this article one specific property of cobar-bar resolution of graded algebra H is shown: any perturbation of differential in this resolution can be "shorten", i.e. it is equivalent to one, which maps the generator module into itself. Any such short perturbation can be interpreted as -algebra structure on H. This allows to obtain some known results about the classification of differential-graded algebras.

Key words: perturbation, bar construction, -algebra.

E. Khmaladze

The Non-Abelian Tensor and Exterior Products Modulo q of Lie Algebras and Related Constructions

Presented by Corr. Member of the Academy H.Inassaridze, December 30, 1998

Abstract. The condition for the existence of a universal q-central relative extension of a Lie epimorphism is given and this extension is described as an exterior product modulo q.

Key words: Lie algebra, crossed module, tensor product, universal extension.



On the Integral Representation of Cauchy’s Problem Solution

Presented by Member of the Academy G. Kharatishvili, September 28, 1998

Abstract. For the ordinary differential equations the point of the representation of the Cauchy’s problem solution as the field function is considered. The integral representation of the solution is received. For this the Riemann’s integral is defined for monoid-valued functions.

Key words: Cauchy’s problem, field, integral representation of solution, directedness, monoid, Lipschitz’s mapping, Riemann’s integral.


V. Jikia

On One Boundary Value Problem

Presented by Corr.Member of the Academy R. Bantsuri, September 28, 1999

Abstract. The boundary value problem (4)-(6)-(7) in the case when the coefficients of Carleman-Vekua equation (4) satisfy the condition (5), is investigated.

Key words: Carleman-Vekua equation, boundary value problem.


I. Dochviri

On Mappings of Bitopological Spaces

Presented by Corr. Member of the Academy N. Berikashvili, May 15, 1999

Abstract. We define (i,j)-S continuous mapping and study some relations of this mapping with respect to: (i,j)-weakly semicontinuous, (i,j)-weakly quasicontinuous, (i,j)-irresolute and (i,j)-q continuous mappings.

Key words: bitopological space; (i,j)-semiopen (semiclosed) set; (i,j)-S continuous, (i,j)- weakly semicontinuous, (i,j)-weakly quasicontinuous, (i,j)-irresolute, (i,j)-q continuous mappings.


A. Liparteliani

Axiomatic Characterization of the Dimension of Closed Mappings of Spaces with Countable Bases

Presented by Corr. Member of the Academy N. Berikashvili, October 26, 1998

Abstract. In the present paper an axiomatic characterization of the
covering dimension of closed mappings is given.

Key words: dimension of mappings, axiomatic characterization, metric spaces.


P.Kervalishvili, M. Khachidze

Artinformatic Knowledge and some Ways of its Presentation

Presented by Member of the Academy V.Chavchanidze, September 21, 1998

Abstract. It is proposed a model for the presentation of artinformation in the form of knowledge, based on the coherent model of brain and a combined method for the presentation of information: the wave-forming presentation of information using fuzzy sets and anticipating fractal nature of artinformation.

key words: artinformation, knowledge base, information presentation models


G.Kekelidze, V.Gogiashvili, Z.Kvinikadze, Z.Davitaya, L.Milovanova, G.Chikhradze, Z.Chubinishvili, G.Papava

The Determination of Free Carrier Absorption Coefficient in
n-type Indium Phosphide from Electrical Measurements

Presented by Corr. Member of the Academy T. Sanadze, July 27, 1998

Abstract. The InP specimens with electron concentration of n~(10 16-
1018) cm-3 at room and liquid nitrogen temperatures were studied. The analysis of experimental results with account of all major scattering mechanisms was carried out . The optical absorption coefficients for each specimen in the infrared range were determined by this data. The index p of the a=alp dependence is shown to be between 2.52-3.3 not tending to 2.

Key words: semiconductor, mobility, absorption coefficient, compensation ratio.


N. Margiani, V. Jgamadze, N. Sabashvili, B. Tabidze, G. Shurgaia, G. Tsintsadze

High-Temperature Superconductivity in the Y-Ba-Ca-Cu-O System

Presented by Member of the Academy G. Kharadze, September 7, 1998

Abstract. The preliminary results of search for high-temperature superconductivity in the Y-Ba-Ca-Cu-O system are presented. Ceramic samples with the YBa2CaxCu3Oy starting composition are found to be superconducting (Tc=81-87K) over the wide range of calcium content x=0,2-2.

Key words: high-temperature superconductivity, Y-Ba-Ca-Cu-O system


V. Kirtskhalia, I.Zhvania, A.Gvelesiani

The Effect of the Curved Surface of Tangential Discontinuity on Kelvin-Helmholtz Hydromagnetic Instability

Presented by Corr. Member of the Academy T. Chelidze, October 19, 1998

Abstract. The problem of the stability of incompressible plasmatic jets of plane and cylindrical configuration is studied. The parameter whose value defines the effect of the geometry of the surface of the tangential discontinuity on the stability of the system is found.

Key words: tangential discontinuity, Kelvin-Helmholtz instability, plasma.


L.Gogorishvili, M.Iordanishvili, T.Kamushadze, E.Keshelava, G.Mirianashvili, Sh.Mirianashvili, A.Matveenko, N.Mirtskhulava, A.Mirtskhulava, R.Shalamberidze, N.Rtveliashvili, K.Edilashvili, L.Khavtasi, R.Maisuradze

Passivation of Infrared Photoreceivers Based on Pb1-xSnxTe with Al2O3 Obtained by Plasma Anodizing Method

Presented by Corr. Member of the Academy T. Sanadze, July 13, 1998

Abstract. Low temperature method of creating protective dielectric Al2O3 with needed properties for lead-tin halcogeniums and for the epitaxial layers of their solid solutions has been worked out. This method is available for making IR-photoreceivers with better properties on the base of Pb1-xSnxTe.

Key words: passivation, anodizing, catalyst.


E. Sakvarelidze, N. Mamulia

Some Results of Investigation of the Heat Regime of the Crust for the Water Area of the Black Sea

Presented by Member of the Academy B.Balavadze, October 12, 1998

Abstract. The deep temperature distribution has been calculated for the water area of the Black Sea. The obtained results are given as temperature maps for the basement of sedimentary cover and surfaces of Conrad and Moho.

Key words: temperature, heat flow, water area of the sea.

Analytical Chemistry

         A.Sirbiladze, Sh.Shatirishvili, I.Shatirishvili

Set of Chromatographic Techniques for Analysing
the Composition of Georgian Wine Materials

Presented by Corr. Member of the Academy A. Shvelashvili, March, 30, 1998

Abstract. A set of different variants of chromatography has been used for the study of Georgian wine materials composition. The determination of the vapour phase composition with 3 detectors as well as the analysis of amino and phenolcarboxylic acids are described.

Key words: wine materials, flame-ionization detector, electron-capture detector, flame-photometric detector.

Analytical Chemistry

Sh. Shatirishvili, T. Maglakelidze

High Performance Capillary Chromatography for Determination of Amines in Wine Materials

Presented by Member of the Academy T. Andronikashvili, September 24, 1998

Abstract. Analysis of amines in white wines "Kakheti"and "Rkatsiteli" was conducted as their derivatives by high performance capillary chromatography method with fluorescent detector.

Key words: high performance capillary chromatography, amines, wines.

General and Inorganic Chemistry

L.Gorjoladze, L.Morchiladze

Synthesis and some Properties of Strontium and Barium Thioindates

Presented by Member of the Academy G.Tsintsadze, May 17, 1999

Abstract. The LiInS2-MeCl2-H2O and Li3InS3-MeCl2-H2O (Me=Sr,Ba) systems have been studied using various physico-chemical methods of investigation: solubility, electroconductivity and pH measurements, roentgenophase and thermographic analysis. It is established that thioindates of corresponding metals with general formula MeIn2S4×2H2O, Me3In2S6×2H2O (Me=Sr,Ba) are produced in systems. Common properties of Sr and Ba thioindates are established. They are characterized by slight solubility in water and alkali, are roentgenoamorphous and thermostable up to 400oC, while above this temprature undergo phase transformation.

Key words: strontium, barium, thioindates.

Organic Chemistry

N.Sidamonidze, L.Janiashvili, L.Tabatadze, L.Bedukadze, M.Tatarishvili, R.Gakhokidze

Synthesis of N-glycosides from a-pyrrolidone and e-caprolactam

Presented by Corr. Member of the Academy L.Khananashvili, July 12, 1999

Abstract. There were synthesized 2,3;5,6-diisopropylidene D-mannofuranosylpyrrolidone (I), 2,3;5,6 diisopropylidene-D-manno-furanosyl caprolactam (II), 2,3,4-tri-O-acetyl-b-L-ramnopyranosylpyrrolidone (III) and 2,3,4-tri-O-acetyl-b-L-ramnopyranosylcaprolactam (IV) of a-chloro-2,3;5,6-diisopropylidene-D-mannofuranose and a-chloro-2,3,4-tri-O-acetyl-L-ramnopyranose by heterofunctional condensation with a-pyrrolidone and e-caprolactam.

Key words: N-glycosides, a-pyrrolidone, e-caprolactam.

Organic Chemistry

D. Tugushi, G. Otinashvili, M. Gverdtsiteli

Algebraic Investigation of the Process of Condensation of Dihydrazide of Isophthalic Acid with Bis-(3-Nitro-


Presented by Corr. Member of the Academy L. M. Khananashvili, October 12, 1998

Abstract. Algebraic investigation of process of condensation of dihydrazide of isophthalic acid bis-(3-nitro-4-chlorophenyl)-sulphone was carried out within the scope of ANB-matrices method.

Key words: condensation, ANB-matrices method.

Organic Chemistry

R.Vardiashvili, R.Gakhokidze, N.Sidamonidze, M.Isakadze, S.Mamulia

Acid Transformation of Toluenesulphonyl Derivatives of D-Fructose

Presented by Corr. Member of the Academy L.Khananashvili, March 1, 1999

Abstract. Under the action of lead hydroxide 1-0-p- toluenesulphonyl-b-D-fructose is converted into 2-deoxy-D-gluconic acid and 3-0-p- toluenesulphonyl-a-D-fructose is converted into a- and b-D-glucometasaccharinic acids.

Key words: acid transformation, D-fructose, 2-deoxy-D-gluconic acid, D-glucometasaccharinic acid.

Chemical Technology

I.Mzhavanadze, J. Nakaidze, N. Papunashvili, N. Sabashvili, G. Tsintsadze,
M. Chubabria

Investigation of the Temperature Dependence of Oxygen Content in the YBa2Cu3O7-x Superconducting Ceramics

Presented by Member of the Academy K. Japaridze, October 26, 1998

Abstract. The preparative method for the high-temperature superconducting YBa2Cu3Oy ceramics having various x values was elaborated.

The character of temperature dependence of the desorbed oxygen and its content have been elucidated. The x, y=f(T) curves exhibit sharp steps at 650-8000C interval. These steps are caused by the endothermic processes of phase transformations.

Key words: high temperature superconductor, YBa2Cu3Oy, oxygen content, quenching, desorption, phase transformation.

Chemical Technology

I. Mikadze, N.Kutsiava

On Reliability of One Duplicated System

Presented by Corr. Member of the Academy A. Prangishvili, August 28, 1999

Abstract. We consider the problem of redundancy of duplicated system reliability indices when approximation of failure stream is possible by general law of Erlang but redundancy time is distributed by general law.

Key words: duplicated system, failure, redundancy.


G.Gavardashvili, I.Kasaburi

Mathematical Model of Landslide Flow Motion

Presented by Member of the Academy G.Svanidze, December 17, 1998

Abstract. The mathematical model of landslide flow motion is constructed with account of main theses of hydromechanics. The computational solution of differential equation permits to determine the landslide flow velocity and distance of propagation taking into consideration both the driving and resistance forces.

Key words: air resistance force; internal fractional force; initial mass.

Structural Mechanics

Corr. Member of the Academy I.Gudushauri

Hydromechanics in Ordinary Differential Equations

Presented July 5, 1999

Abstract. A new theory has been put forward, by which the solution of hydromechanical problems can be reduced to integration of ordinary differential equations without any additional hypothetical assumptions. It is based on the theory of elasticity in ordinary differential equations instead of classical theory of elasticity applied in classical hydromechanics.

Key words: hydromechanics, partial differential equations, liquid pressure, viscosity.

Exploitation and Concentration of Deposits

V.Gvakharia, T.Sharabidze, E.Kirkesali, R.Chkhaidze

Determination of Metal Flow in Pulp by Neutron Activation Method

Presented by Corr. Member of the Academy I.Baratashvili, November 30, 1998

Abstract. With utilization of achievement in nuclear physics the method has been created for automatic determination of metal flow in the manganese pulp. The automatic controlling computer system has been proposed to the technological processes of the manganese flotation concentration.

Key words: detector, computer, reagents, controlling module

Machine Building Science

A. Gogava

Automation of Calculation of Rigid Body Systems Vibrations

Presented by Member of the Academy R.Adamia, December 21, 1998

Abstract. Calculation of rigid body system vibrations connected with elastic links using finite element method is considered.

Key words: vibrations, finite element method.

Machine building science

V. Menteshashvili

Optimization of High-Temperature Steels Cutting Processes Using Plasma-Arch Heating

Presented by Member of the Academy T. Loladze, January 25, 1999

Abstract. The work is related to the cutting process of the high-temperature and hard steel items using plasma-arch preheating. The optimization indices are obtained using the method of experimental planning. The mathematical model in the form of the equation of regression which adequately describes the ongoing process regarding all acting factors was developed. The effect of individual indices on the wear intensity of the cutting tool was studied; general conclusions were made based on the obtained results.

Key words: plasma-arch, high-temperature, loss of strength, coded indices, experiment planning, equation of regression, wear intensity, optimization of indices.

Automatic Control and Computer Engineering

R.Khurodze, R.Kakubava, L.Sikharulidze

Some Problems of Redundant Systems Reliability Modelling

Presented by Corr. Member of the Academy A.Prangishvili, October 5, 1999

Abstract. A generalized mathematical model of duplicated system is constructed as convolution type integral equation. Its solution is given in Laplace expression terms for one of the most interesting cases. Engineering-heuristic method is proposed for researching of asymptotic behavior of the system.

Key words: failure, renewal, stochastic process.



The Fodder Crops' Roots Productivity on the Southern Slope of the Saguramo-Yalno Ridge, according to the Farming-Botanical Fractions

Presented by Corr. Member of the Academy P. Naskidashvili, December 21, 1998

Abstract. The mass volume of fodder crops' roots productivity of the southern slope of the Saguramo-Yalno ridge was investigated. These crops are distributed on the slopes of oak and beech forests, where the secondary post-forest valleys are developed.

Key words: cereals, leguminous plants, sedge, vary-grasses, moss, lichen, residues

Plant Physiology

N. Datukishvili, T. Barblishvili, Sh. Chanishvili, Sh. Dzagnidze

Effect of Partial Defoliation and Benzylaminopurine on Content
of Free Amino Acids in Shoot Organs of Grapevine

Presented by Corr.Member of the Academy N.Nutsubidze,October 12,1998

Abstract. The influence of partial defoliation and BAP on content of free amino acids in leaves, stems and berries of grapevine has been studied. The enhancement of source activity under defoliation and of sink demand under the BAP influence were accompanied with a quantitative increase of free amino acids in organs of grapevine shoot. The combined action of defoliation and BAP is more effective and it is probably associated with the increase of free amino acids biosynthesis in leaves.

Key words: defoliation, benzylaminopurine, amino acids, grapevine.

Plant Growing


Agrobiological and Technological Indices of Vine "Gorula"

Presented by Corr. Member of the Academy P.Naskidashvili, September 14, 1999

Abstract. Vitis variety "Gorula" is characterized by high quality and yielding ability. It is advisable to develop it in the environs of Tbilisi city.

Key words: table vine.

Genetics and Selection

Kh. Gamkrelidze, N. Zarnadze, M. Gogoberidze

Influence of Auxins on Shoot Regeneration and Rooting during Stevia raboudiana Microclonal Propagation

Presented by Member of the Academy G. Kvesitadze, September 14, 1998

Abstarct. The influence of auxins - naphtylacetic acid and indole butyric acid on shoot regeneration and rooting processes during Stevia raboudiana microclonal propagation was studied. Meristemic regeneration occurred much better when using 3-6 mM indole butyric acid. This auxin was successful for rooting of stevia regenerates as well.

Key words: microclonal propagation, Stevia raboudiana, auxins, shoot regeneration.

Genetics and Selection

G.Dumbadze, Sh.Goliadze

Peculiarities of Form Creation during Mandarin Chemical

Presented by Corr. Member of the Academy P.Naskidashvili, May 17, 1999

Abstract. We have studied variability types and frequency in generation obtained as a result of chemical mutagenesis, nitrosoethyl carbamide (NEC) effect on seeds of Citrus unschiu Marc.

Key words: mandarin, mutagenesis.

Genetics and Selection

R.Gakhokidze, A. Pirtskhelani

Comparative Assessment of Antimutagenic Action of Ragozan and a-Tocopherol in Phosphamide-Induced Mutations

Presented by Member of the Academy G. Kvesitadze, February 27, 1999

Abstract. The comparative study of antimutagenic properties of Ragozan and a-tocopherol was carried out on the laboratory mice. Phosphamide (general pesticide) was used as a mutagenic agent. The bone marrow cells were investigated cytogenetically. It was found that antimutagenic efficacy of Ragozan is significantly higher than that of a-tocopherol.

Key words: environment, mutagens, antimutagens, cytogenetics, mice.

Human and Animal Physiology

E. Vekua

Rearing Reaction Dynamics during Development of the
Informational Pathology of the Higher Nervous Activity in Rats

Presented by Corr. Member of the Academy V. Mosidze, December 28, 1998

Abstract. The higher nervous activity of the albino rats was investigated by the method of the defensive conditional reflexes (active avoidance) during various stages of development of the experimental informational neuroses. On the basis of analysis of the rearing reaction dynamics, the above reaction is estimated not as a self-regulation behavior but as an index of emotional tension.

Key words: informational pathology of the higher nervous activity, rearing, emotional tension, rats.

Human and Animal Physiology

Member of the Academy T.Oniani, L.Maisuradze, N.Lortkipanidze, M.Mgaloblishvili, E.Chidjavadze, L.Oniani, N.Oniani, M.Babilodze

Total Paradoxical Sleep Deprivation through Partial Deprivation of Slow-Wave Sleep

Presented May 24, 1999

Abstract. Analysis of the results of total paradoxical sleep deprivation (PSD) through partial deprivation of deep slow-wave sleep (DSWS) clearly indicates that the formation of PS need in the sleep-wakefulness (S-W) cycle occurs exclusively during SWS and especially during DSWS. The phase of wakefulness cannot be involved in PS need accumulation. On the contrary, it someway prevents PS need accumulation even in that case when its fragments arise during SWS. These data are in conformity with our earlier evidence that the replacement of PS in the cycle by the fragments of active wakefulness equivalent in length to mean PS duration, leads to a complete and selective PS deprivation without accumulation of the need for it. In a normal S-W cycle wakefulness and PS appear to be competitive and in this competition it is wakefulness that has an advantage. This is perhaps reasonable and necessary for a precise determination of the place of PS in the S-W cycle. Otherwise there would be disturbance of the normal integrative activity of the brain and disruption of the S-W cycle that not infrequently manifest itself in a number of psychoneurologic diseases.

Key words: paradoxical sleep, slow-wave sleep, sleep-wakefulness cycle, deprivation, accumulation,need.


E.Avaliani, M.Melikishvili, T.Eristavi, G.Berishvili, G.Mikadze, Member of the Academy M.Zaalishvili

The Study of Possibility of Nebulin Extraction by the High Ionic Strength Buffers Traditional for the Extraction
of Myofibrillar Proteins

Presented August 6, 1998

Abstract. The experiments for selection of conditions for native nebulin extraction were carried out. According to our results the possibility of native nebulin extraction with high ionic strength buffers traditional for the extraction of myofibrillar proteins (Weber, Hasselbach-Schneider and Guba-Straub) in which the full complex of protease inhibitors had been added to prevent degradation of giant proteins (titin and nebulin) has not been proved.

Key-words: nebulin, titin, immunoblotting.


G. Kharebava, T. Garishvili, D. Mikeladze, Corr. Member of the Academy
V. Bakhutashvili

Chromatographic Characterization of Plaferon LB

Presented November 3, 1998

Abstract. Georgian-made antiviral and immunomodulative remedy Plaferon LB was investigated by different chromatographic approaches. Attempts were undertaken to obtain primary biochemical data by HPLC and to scale up prepurification methods for testing on bioactivity in different model systems. To find out purified bioactive substance being of crucial importance, we prepared simplified fractions for further accurate testing.

Key words: placental factors; HPLC; drugs.


V. Philauri, N. Surguladze, K.Kutalia, D. Margiani, G.Zaalishvili, Corr. Member of the Academy T. Zaalishvili

Changes of the Rat Brain and Liver Cell Nuclear Matrices Poly (ADP-ribose) Polymerase and DNA Topoisomerase II
Activities by X-irradiation

Presented October 12, 1998

Abstract. It is shown, that X-irradiation of isolated rat brain and liver matrices at the doses of 1.7 Gy and 6.7 Gy increases their endogenous poly(ADP-ribose) polymerase activity in a dose-dependent manner. This indicates that the breaks induced in DNA tightly bound with matrices is a reason for poly(ADP-ribose) polymerase activity increasing. It is revealed also, that DNA topoisomerase II activity of the isolated matrices of both brain and liver cells is inhibited after X-irradiation of rats as compared to control matrices isolated from nonirradiated rats. This testifies to the involvement of DNA topoisomerase II activity in DNA repair and gives possibility to suppose that the induction of ADP-ribosylation directly of DNA topoisomerase II in vivo after X-irradiation of rats decreases topoisomerase activity of isolated matrices.

Key words: brain, liver, nuclei, nuclear matrix, X-irradiation, poly(ADP-ribose) polymerase, DNA topoisomerase.

Microbiology and Virology


Study of Tuberculostatic Activity of Honey by Dilution Method

Presented by Member of the Academy T. Chanishvili, July 27, 1998

Abstract. In vitro experiments have shown that honey has a clear-cut tuberculostatic activity. In liquid nutrition medium this antibacterial activity of honey manifests itself at 1:16 dilutions.

Key words: M. tuberculosis, honey, bacteriostatic, multiresistance.


M. Kalatozishvili

Variation of Microelements and Ribonucleic Acid in Neurons from Various Rat Brain Areas during Two-Month and Acute Alcoholic Intoxication

Presented by Member of the Academy T. Oniani, December 14, 1998

Abstract. Studies have shown that a prolonged alcohol injection results in a rise of RNA amount in the neurons of sensorimotor and motor cortices and an increase in concentration of zinc and iron ions in the hippocampal nerve cells.

Key words: alcohol, intoxication, RNA, zinc, iron.



Comparative Characteristics of Pseudounipolar and Motor Neurocytes in Dog’s Anterior Horn in Experiment

Presented by Member of the Academy T.Chanishvili, September 20, 1999

Abstract. Morphometric criteria of spinal cord and corresponding spinal ganglia of neurocytes density and compactness have been established.

Key words: motoneurocyte, pericarion, neurocyte pseudounipolar.

Experimental Medicine

E.Meskhishvili, P.Ivanyi, E.Ivaskova, C.Dostal, D.Charron, E.Albert, C.Marie

The Promoter QAP and QBP Alleles in Czech Population and Rheumatoid Arthritis Multicase Families

Presented by Member of the Academy K.Nadareishvili, July 6,1998

Abstract.. HLA promoter alleles of DQA1 and DQB1 genes were analyzed in a group of 65 Czech healthy individuals and 54 members of 13 RA multicase families by PCR and oligonucleotide hybridization. QAP4.1 and QBP3.1 were the most frequent alleles (gf=0.315, gf=0.254) due to the linkage disequilibrium with DQA1*0501 and DQB1*0301. The second most frequent allele QAP1.2 (gf=0.162) was found to be common for DR2 alleles.The analysis of RA multicase families showed promoter alleles and haplotypes similar to those reported in the healthy population. QBP3.21 was in a complete positive association with DQB1*0302-DRB1*04, except DQB1*0302-DRB1*0408, where was detected QBP3.1, associated also with DQB1*0301-DRB1*0401. Promoter polymorphism may reflect a level of expression and function of HLA structural alleles.

Key words: promoter alleles, HLA, rheumatoid arthritis.

Experimental Medicine

K. Gogilashvili

The Ratio of Genetic and External Factors in Ethiopathogenesis of Decompensated Caries

Presented by Member of the Academy T.Dekanosidze, November 9, 1998

Abstract. Based on results of clinical-genealogical and genetic research of 162 ethnic Georgian control probands and of 178 cases of decompensated caries, by applying genetic-mathematical methods, it has been determined that inherited inclination towards disease corresponds to alternative distribution of phenotypic model. Within the framework of this model the correlation between parents and children equals 0.429.

The ratio of additive-genetic component (Ga) equals 85.8%, and the ratio of environmental components (Ew) is 14.2%.

Key words: genetic factor, environmental factor, decompensated caries, alternative distribution, phenotypic dispersion.

Experimental Medicine

R.Rukhadze, T.Chikovani, Corr. Member of the Academy V.Bakhutashvili, T.Sanikidze, D.Metreveli, I.Pantsulaia, M.Balarjishvili

Influence of Plaferon LB on the Metabolism of Nitric Oxide (NO) in Case of Hypothyroidizm

Presented November 9, 1998

Abstract. Nitric oxide metabolism during hypothyroidizm and influence of Plaferon LB on it in experimental hypothyroidizm was studied. In the case of Hashimoto’s disease, as well as in experimental hypothyroidizm the increased formation of nitric oxide takes place that indicates the formation of large amount of free radicals. Plaferon LB prevents redundant formation of nitric oxide during experimental hypothyroidizm and facilitates its quick decrease during the period of restoration.

Key words: nitric oxide, Plaferon LB, hypothyroidizm, electronic paramagnetic resonanse (EPR).

Experimental Medicine

A.Koridze, Corr. Member of the Academy V.Bakhutashvili

Some Parameters of Immune System in Pregnant Women with Heavy Nephropathy and its Immunocorrection by Plaferon-LB

Presented January 29, 1999

Abstract. Introduction of Plaferon-LB a protein-peptide preparation isolated from human placental amnion-chorionic membrane - into the therapy of pregnant women afflicted by the heavy nephropathy and subjected to the Ceasarean section, has shown to improve the immune disorders characteristic for the above pathology.

Key words: pregnancy nephropathy, immunocorrection, Plaferon-LB.

Experimental Medicine

R. Javakhadze

Some Prognostic Peculiarities of Occupational Effect of Manganese

Presented by Corr.Member of the Academy N.Tatishvili, August, 23, 1999

Abstract. The study of simultaneous action of harmful chemical and physical factors, its mechanisms and obtained results is the most actual problem of preventive medicine. The solution of these problems helps in the formation of a new conception.

Key words: occupational disease, manganese, manganoconiosis, vibration, harmful effects, parkinsonizm, chronic intoxication, accompanied pathology, informative diagnostic criteria.

Experimental Medicine

I.Topuria, K.Natmeladze

The Role of Prolactin and Gonadotropins Cyclic Secretion during Formation of Intellectual Possibilities in Adolescent Girls being in Pubertal Period

Presented by Corr. Member of the Academy T.Dekanosidze, June 17, 1999

Abstract. We have examined adolescent girls being in pubertal period. Two clinical groups have been isolated which underwent prolactin and gonadotropin control. It was established that the cyclicity of prolactin and gonadotropin secretion can be broken in conditions of wrong demands in regards to girl’s intellectual potential if psychological and sexual states are not taken into account.

Key words: prolactin, gonadotropin.



On the Term "Metalanguage"

Presented by Corr. Member of the Academy A. Gvakharia, October 12, 1998

Abstract. The concept of "metalanguage" plays a noticeable part in the traditional linguistic theories. Having analysed the accepted definitions of the term we came to the conclusion that the concept is non-formalizable within the limits of linguistics and therefore it turns out void of function in linguistic researches.

Key words: content, expression, metasemiotics, interpreter.

History of Art


On Bidzina Kvernadze‘s Orchestra

Presented by Member of the Academy V.Beridze, July 20, 1998

Abstract. Form formation function of Kvernadze’s orchestra is well expressed in his texture development. Composer realizes individualization of his polymelodic texture through timbre equality. He frequently uses timbre differentiation of multielement ostinato. Timbre affects greatly the theme development process not only in development part of sonata form itself but also in its reprise. Orchestra role is significant in the development of variation form. Dramatic role of orchestra timbres is especially remarkable in ballet or in theatre and stage genres.

Key words: unison, polymelodizm, contrapunkt, ostinato, sonorit y, cluster.